Situational Confidence and Recovery Capital Among Recovery Residents Taking Medications for Opioid Use Disorder in Texas 🔓
Journal of Addiction Medicine
Situational confidence (SC) is the confidence of one to resist substance use when in high-risk situations, while recovery capital (RC) are the resources that support persons in recovery and can be drawn upon by those persons. The authors conducted a cross-sectional study to evaluate associations between total, social, and personal RC and SC. In the multivariate analysis, they found higher education and higher personal, social, and total RC were all associated with higher SC. While the authors do note that patients in this study had relatively high SC overall, they support assessing RC and SC of patients to help guide decisions about treatment needs and intensity of support. The authors also note further research is needed to evaluate SC and RC over time in the recovery process.
Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking
Cocaine use disorder represents a public health crisis with no FDA-approved medications for its treatment. A growing body of research has detailed the important connections between the brain and the resident population of bacteria in the gut -- the gut microbiome -- in psychiatric disease models. Acute depletion of gut bacteria results in enhanced reward in a mouse cocaine place preference model, and repletion of bacterially-derived short-chain fatty acid (SCFA) metabolites reverses this effect. In the absence of a normal microbiome, repletion of bacterially-derived SCFA metabolites reversed the behavioral and transcriptional changes associated with microbiome depletion. These findings suggest that gut bacteria, via their metabolites, are key regulators of drug-seeking behaviors, positioning the microbiome as a potential translational research target.
Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder in the US, 2021 🔓
JAMA Network Open
Data on prevalence of MOUD receipt among persons with OUD in the US are limited. Using data from the 2021 National Survey on Drug Use and Health (NSDUH), this study sought to provide rates of MOUD receipt among adults with past-year OUD. Among the estimated 2.5 million persons with OUD in the past year, 22.3% received MOUD. Groups least likely to receive treatment included Black adults, women, the unemployed, and those living outside of metropolitan areas. Conversely, receiving telehealth services was associated with an increased likelihood of receiving MOUD, emphasizing its critical place in accessing treatment.